1093276-09-5

BMS-641988 (compound 23) is an oral active nonsteroidal androgen receptor antagonist with the Ki of 1.7 nM. BMS-641988 shows anticancer activity[1].

ChEBI: N-[(3aR,4R,5R,7R,7aS)-2-[4-cyano-3-(trifluoromethyl)phenyl]-4,7-dimethyl-1,3-dioxo-3a,5,6,7a-tetrahydro-octahydro-1H-4,7-epoxyisoindol-5-yl]ethanesulfonamide is an organonitrogen compound and an organooxygen compound. It is functionally related to a delta-amino acid.

[1] Balog A, et al. Discovery of BMS-641988, a Novel Androgen Receptor Antagonist for the Treatment of Prostate Cancer. ACS Med Chem Lett. 2015;6(8):908-912. Published 2015 Jun 19. DOI:10.1021/acsmedchemlett.5b00173