Ro 31-8588 is a hydroxyethylene inhibitor of HIV protease.
Uses
Ro 31-8588 is a HIV protease inhibitor with the Ki of 0.3 nM. Ro 31-8588 can be used for study of AIDS[1].
References
[1] Graves BJ, et al. The three-dimensional x-ray crystal structure of HIV-1 protease complexed with a hydroxyethylene inhibitor. Adv Exp Med Biol. 1991;306:455-60. DOI:10.1007/978-1-4684-6012-4_58
