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Amino acid derivative useful for the treatment of Alzheimer disease.

Amino acid derivative useful for the treatment of Alzheimer's disease.

(S)-N-Boc-L-homoserine ethyl ester is a synthetic intermediate in the synthesis of unsaturated caprolactams and monomer units for oxy-peptide nucleic acids from the starting material L-homoserine.

[1] JACOB M. JANEY. Raney-Co Mediated Reductive Cyclization of an α,β-Unsaturated Nitrile[J]. The Journal of Organic Chemistry, 2008, 73 8: 3212-3217. DOI: 10.1021/jo8000996
[2] MASAYASU KUWAHARA  Masahiko S ?  Miki Arimitsu. Synthesis of δ-amino acids with an ether linkage in the main chain and nucleobases on the side chain as monomer units for oxy-peptide nucleic acids[J]. Tetrahedron, 1999, 55 33: Pages 10067-10078. DOI: 10.1016/s0040-4020(99)00541-4