1926163-82-7

Mca-PLAC(p-OMeBz)-WAR(Dpa)-NH₂ is a fluorogenic substrate for matrix metalloproteinase-14 (MMP-14).¹ Upon cleavage by MMP-14, 7-methoxycoumarin-4-acetyl (Mca) is released and its fluorescence can be used to quantify MMP activity. Mca displays excitation/emission maxima of 328/420 nm, respectively.

Mca-Pro-Leu-Ala-Cys(Mob)-Trp-Ala-Arg-Dap(Dnp)-NH2 is a fluorogenic substrate for matrix metalloproteinase-14 (MMP-14).

MMP-14

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1. Eckhouse, S.R., Akerman, A.W., Logdon, C.B., et al. Differential membrane type 1 matrix metalloproteinase substrate processing with ischemia-reperfusion: Relationship to interstitial microRNA dynamics and myocardial function J. Thorac. Cardiovasc. Surg. 145(1),267-275(2013).