ChemicalBook CAS DataBase List 425642-32-6

425642-32-6

Name	GPI choline
CAS	425642-32-6
Molecular Formula	C14H32NO12P
Molecular Weight	437.38
MOL File	425642-32-6.mol

Chemical Properties

Cosmetics Ingredients Functions	SKIN PROTECTING
InChIKey	PTZZCYHESHNXFL-MFJCNYFVNA-M
SMILES	C(CO)[N+](C)(C)C.O([C@@H]1[C@@H]([C@H](O)[C@@H](O)[C@H](O)[C@H]1O)O)P([O-])(=O)OC[C@H](O)CO \|&1:8,9,10,12,14,16,24,r\|

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Animal Model:	Postoperative pain model of female C57/Bl6 mice^[2]
Dosage:	0.2 and 100 mg/kg/h
Administration:	Subcutaneous injection, 24 or 48 hours
Result:	Reduced heat hypersensitivity after surgery with maximal efficacy after 48 h treatment and the ED₅₀ value of choline dose was 1.7 mg/kg/h. Reduced hypersensitivity to punctate mechanical stimuli 48 hours after infusion in a dose-dependent manner and with the ED₅₀ value of 4.7 mg/kg/h but not 24 hours.

425642-32-6

Chemical Properties

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in vivo

IC 50

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