609-67-6

white to pinkish or pale yellow crystalline

2-Iodobenzoyl chloride has been used in palladium-catalyzed synthesis of carbomethoxy functional group-induced isoindolin-1-ones, preparation of starting materials required for the synthesis of novel cyclic derivatives of pentavalent iodine, benziodazole oxides.

General method: 2-iodobenzoic acid (1.0 mmol) was mixed with excess thionyl chloride (5 mL) and reacted at reflux for 2 hours. Upon completion of the reaction, the excess thionyl chloride was removed by vacuum concentration to give o-iodobenzoyl chloride in quantitative yield.

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