BAY 1217224 is a neutral, non-proagent Thrombin inhibitor with good oral pharmacokinetics.
References
[1] Hillisch A, et al. Design, Synthesis, and Pharmacological Characterization of a Neutral, Non-Prodrug Thrombin Inhibitor with Good Oral Pharmacokinetics. J Med Chem. 2020 Nov 12;63(21):12574-12594. DOI:10.1021/acs.jmedchem.0c01035