Chemical Properties
Type R (i.e. D): crystalline, melting point 240°C (decomposition), [α]-158.4° (C=1,1 mol/L HCl). (+/-) type: lamellar crystals (water), insoluble in water, insoluble in ether, 200°C non-melting decomposition.
Uses
4-hydroxyphenylglycine is used (now only rarely) as a photographic developer and in
the determination of phosphorus and silicon.
Uses
(4-Hydroxyphenyl)glycine, is a key intermediate for the synthesis Cefpiramide (C243400), used as a β-lactam antibiotic.
Definition
ChEBI: 4-hydroxyphenylglycine is a glycine molecule carrying a 4-hydroxyphenyl substituent. It has a role as a bacterial metabolite. It is functionally related to a glycine.
Synthesis Reference(s)
Journal of the American Chemical Society, 93, p. 2897, 1971
DOI: 10.1021/ja00741a013