(R)-METHYL BOPHOZ(TM)

Reaction

1. Ligand used in the rhodium-catalyzed, asymmetric hydrogenation of β-amido-vinylphosphonates.
2. Ligand used in the rhodium or iridium-catalyzed asymmetric hydrogenation of α,β-unsaturated esters.

Chemical Properties

Uses

• As an efficient ligand for asymmetric hydrogenation reactions.
• To synthesize a single enantiomer of cyclopropylalanine via hydrogenation reaction using rhodium catalyst.
• To prepare chiral phenylalanine derivatives from α-amido cinnamic acids (or esters) using rhodium catalyst.