Description
AUN-54398 is a phospholipid that contains stearic acid and adrenic acid at the sn-1 and sn-2 positions, respectively. This product has no formal name.
Uses
1-Stearoyl-2-Adrenoyl-sn-glycero-3-PC (PC(18:0/22:4)) is an inhibitor of cyclin-dependent kinases (CDKs). 1-Stearoyl-2-Adrenoyl-sn-glycero-3-PC induces apoptosis and inhibits the growth of various cancer cell lines[1].
Definition
ChEBI: 1-octadecanoyl-2-(7Z,10Z,13Z,16Z-docosatetraenoyl)-sn-glycero-3-phosphocholine is a phosphatidylcholine 40:4 in which the two acyl substituents at positions 1 and 2 are specified as stearoyl and (7Z,10Z,13Z,16Z)-docosatetraenoyl respectively. It has a role as a mouse metabolite. It is functionally related to an octadecanoic acid and an all-cis-docosa-7,10,13,16-tetraenoic acid.
References
[1] Bell, M. V., et al. Molecular Species Composition of the Major Diacyl Glycerophospholipids from Muscle, Liver, Retina and Brain of Cod (Gadus morhua). Lipids, 26(8), 565–573.
