Amustaline Dihydrochloride Chemical Properties,Usage,Production
Uses
Ex-vivo blood bank process for inactivation
of viruses, bacteria, parasites, and leukocytes in
red blood cells (nucleic acid alkylator).
in vivo
S‐303 RBCs (a single transfusion) is well tolerated in rats (50 μmol/kg) and dogs (70 μmol/kg)[3].
S‐303 RBCs (repeated transfusions) is well tolerated in rats (10 μmol/kg) and dogs (10 μmol/kg) with no histopathologic evidence of organ toxicity[3].
