beta-endorphin (6-31)
- Product Namebeta-endorphin (6-31)
- CAS77761-27-4
- CBNumberCB41394797
- MFC131H218N34O40
- MW2909.36
- MOL File77761-27-4.mol
Chemical Properties
| Boiling point | 2671.5±65.0 °C(Predicted) |
| Density | 1.294±0.06 g/cm3(Predicted) |
| Sequence | Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-Tyr-Lys-Lys-Gly-Glu |
beta-endorphin (6-31) Price
| Product number | Packaging | Price | Product description | Buy |
|---|---|---|---|---|
| Biorbyt Ltd orb364362 | 1mg | $479.4 | Beta-Endorphin (6-31) > 95% |
Buy |
| Biorbyt Ltd orb364362 | 5mg | $1016.6 | Beta-Endorphin (6-31) > 95% |
Buy |
| Biorbyt Ltd orb364362 | 10mg | $1518.1 | Beta-Endorphin (6-31) > 95% |
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beta-endorphin (6-31) Chemical Properties,Usage,Production
Uses
β-Endorphin, an endogenous opioid neuropeptide, is an opioid receptor agonist. β-Endorphin binds preferentially to μ-opioid receptors and is produced in certain neurons of the central and peripheral nervous system and is one of three endorphins produced in humans. β-Endorphin can be used to reduce stress and maintain homeostasis in the body and is involved in neurological pain perception regulation[1].in vivo
β-Endorphin (0.03 to 1.00μg/kg, i.p., once) impairs retention of a one-trial inhibitory avoidance task in a dose-dependent manner in male Swiss mice immediately post-training. Also, it works in the process of memory consolidation[1].
| Animal Model: | Adult male Swiss mice (22-25 g)[1] |
| Dosage: | 0.03, 0.10, 0.30 or 1.00 μg/kg |
| Administration: | i.p., once |
| Result: | Significantly impaired retention at the doses of 0.03 and 0.10μg/kg while not significantly affect retention as compared with the control group at the two higher doses of 0.30 and 1.00μg/kg , but tended to increase retention as compared with the dose of 0.10μg/kg. Increased latencies to step-through at the two higher doses of 0.30 and 1.00μg/kg but no effect at lower doses. |
References
[1] Introini IB, et al. The impairment of retention induced by beta-endorphin in mice may be mediated by a reduction of central cholinergic activity. Behav Neural Biol. 1984 Jul;41(2):152-63. DOI:10.1016/s0163-1047(84)90527-2Preparation Products And Raw materials
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