Synthesis
Triphenylphosphine (15.00 g, 57.25 mmol) and dibromomethane (19.92 g, 114.48 mmol) were dissolved in dry toluene (125 mL). The reaction mixture was heated to reflux for 7 days. Upon completion of the reaction, the mixture was cooled to 0 °C, the precipitated white crystals were collected by filtration and washed with toluene to give the final bromomethyltriphenylphosphonium bromide (16.50 g, 66% yield).
References
[1] Journal of Organic Chemistry, 2000, vol. 65, # 24, p. 8180 - 8187
[2] Journal of the American Chemical Society, 2005, vol. 127, # 41, p. 14182 - 14183
[3] Chemistry - A European Journal, 2010, vol. 16, # 19, p. 5803 - 5811
[4] Journal of Organic Chemistry, 2012, vol. 77, # 5, p. 2149 - 2158
[5] Tetrahedron, 2003, vol. 59, # 7, p. 1021 - 1032
