Synthesis
GENERAL STEPS: Pyrazole (1 eq.) and triethylamine (1.5 eq.) were dissolved in dichloromethane (for 0.05 mol pyrazole, 50 mL of dichloromethane was used), followed by the addition of di-tert-butyl dicarbonate (1.2 eq.). The reaction mixture was stirred overnight at room temperature. Upon completion of the reaction, the organic phase was washed with saturated NaHCO3 solution (25 mL, against 50 mL of dichloromethane), and then once more with deionized water (25 mL). The organic layer was dried with anhydrous Na2SO4 and subsequently concentrated under reduced pressure to give tert-butyl 1H-pyrazole-1-carboxylate.
References
[1] Tetrahedron Letters, 2006, vol. 47, # 43, p. 7551 - 7556
[2] Chemistry - A European Journal, 2016, vol. 22, # 28, p. 9687 - 9692
[3] Arkivoc, 2014, vol. 2014, # 6, p. 54 - 71
