Description
rac-N-desmethyl Ivabradine-d6 is intended for use as an internal standard for the quantification of N-desmethyl ivabradine (Item No. 27808) by GC- or LC-MS. N-desmethyl Ivabradine is an active metabolite of ivabradine (Item No. 15868).1 Ivabradine is metabolized by the cytochrome P450 (CYP) isoform CYP3A4.WARNING This product is not for human or veterinary use.
References
[1] GIAN MARCO ROSA. An evaluation of the pharmacokinetics and pharmacodynamics of ivabradine for the treatment of heart failure.[J]. Expert Opinion on Drug Metabolism & Toxicology, 2014, 10 2: 279-291. DOI:
10.1517/17425255.2014.876005
