LNK01004

Uses

LNK01004 is a JAK inhibitor with strong inhibitory effects on JAK1 (IC50: 10 nM), JAK2 (IC50:＜0.51 nM) and TYK2 (IC50: 1.0 nM) . LNK01004 can simultaneously inhibit multiple cytokine-induced p-STAT signaling pathways. LNK01004 can be used in the research of diseases such as atopic dermatitis[1].

References

[1] Gao YJ, et al. Crystal form of pyrazolyl-amino-pyrimidinyl derivative, and preparation method therefor and use thereof. WO2023151724A1. 2023-08-17.