urdamycin B

Uses

Urdamycin B is an antibiotic that effectively inhibits fungi and bacteria. Urdamycin B also exhibits anti-proliferative activity against mouse leukemia cells L1210. Urdamycin B can be obtained from the metabolic products of Streptomyces fradiae. Urdamycin B can be used for research on cancer as well as bacterial and fungal infections[1][2].

Definition

ChEBI: Urdamycin B is an oligosaccharide.

Biological Activity

Urdamycin B is a glycoside bacterial metabolite that has been found in S. fradiae and has antibacterial and anticancer activities.1 It is active against Gram-positive and Gram-negative bacteria and inhibits proliferation of L1210 leukemia cells (IC50 = 2.4 μg/ml).

References

1.Drautz, H., Zhner, H., Rohr, J., et al.Metabolic products of microorganisms. 234. Urdamycins, new angucycline antibiotics from Streptomyces fradiae. I. Isolation, characterization and biological propertiesJ. Antibiot. (Tokyo)39(12)1657-1669(1986)