Description
10(E)-Pentadecenoic acid is a 15-carbon, long-chain monounsaturated fatty acid. It inhibits IFN-γ-induced production of kynurenine in THP-1 cells by 14% when used at a concentration of 20 μM. 10(E)-Pentadecenoic acid has been used in studies of alternative β-oxidation pathways.
Uses
(10E)-10-Pentadecenoic Acid, is a monounsaturated fatty acid, and the trans isomer of myristoleic acid. Myristelaidic acid is converted to myristelaidoyl CoA at a faster rate than myristoleic acid to myristoleoyl CoA.
Definition
ChEBI: 10-pentadecenoic acid is a pentadecenoic acid having its double bond in the 10-position.
References
[1] JULIEN ROBERT . Analysis of the β-oxidation of trans-unsaturated fatty acid in recombinant Saccharomyces cerevisiae expressing a peroxisomal PHA synthase reveals the involvement of a reductase-dependent pathway[J]. Biochimica et biophysica acta. Molecular and cell biology of lipids, 2005, 1734 2: Pages 169-177. DOI:
10.1016/j.bbalip.2005.02.010[2] L ALLENBACH Y P. Analysis of the alternative pathways for the beta-oxidation of unsaturated fatty acids using transgenic plants synthesizing polyhydroxyalkanoates in peroxisomes.[J]. Plant Physiology, 2000, 124 3: 1159-1168. DOI:
10.1104/pp.124.3.1159
