METHYL 2-(CHLOROMETHYL)NICOTINATE

Uses

Methyl 2-(chloromethyl)nicotinate is an intermediate used in synthesizing NAI 1 (N215005), which is used in the process of visualizing the physical basis for molecular behavious inside living cells. RNAs are central to biological regulation and this molecule aids in the first global view of RNA secondary structures in living cells for all four bases.

Synthesis

Methyl 2-chloromethylpyridine-3-carboxylate can be obtained by chlorination from methyl 2-methylnicotinate. It has been reported in the literature that it can be used to prepare a TLRs agonist.