Avatrombopag hydrochloride

Chemical Properties

form	Solid
color	Off-white to gray

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Animal Model:	NOD/SCID mice (transplanted with human FL CD34+cells)^[1]
Dosage:	0.3, 1, and 3mg/kg
Administration:	P.o.; daily for 14 days
Result:	Dose-dependently increased the number of human platelets, resulting in approximately a 2.7‐fold increase at 1 mg/kg/d and a 3.0-fold increase at 3 mg/kg/d on day 14 after the start of administration.