LY593093 is a selective, orally active, and brain-penetrant muscarinic M1 receptor agonist with an EC50 of 22.8 nM. LY593093 can be utilized in Alzheimer’s disease research[1].
References
[1] Liu B, et al. Design and synthesis of N-[6-(Substituted Aminoethylideneamino)-2-Hydroxyindan-1-yl]arylamides as selective and potent muscarinic M agonists. Bioorg Med Chem Lett. 2015 Oct 1;25(19):4158-63. DOI:10.1016/j.bmcl.2015.08.011