7-demethylsuberosin

Yellow crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO. It comes from Korean Angelica sinensis and the Dai medicine Tripterygium wilfordii.

Demethylsuberosin (7-Demethylsuberosin) is a coumarin compound isolated from Angelica gigas Nakai, and has anti-inflammatory activity[1].

ChEBI: A natural product found in Citropsis articulata.

[1] Yongfen Ma, et al. Anti-inflammatory Activities of Coumarins Isolated from Angelica gigas Nakai on LPS-stimulated RAW 264.7 Cells. J Food Sci Nutr Vol 14, p 179～187 (2009).
[2] Yang X, et al. Angelica decursiva exerts antihypertensive activity by inhibiting L-type calcium channel. J Ethnopharmacol. 2023 Sep 15;313:116527.
[3] Kang SY, et al. Neuroprotective coumarins from the root of Angelica gigas: structure-activity relationships. Arch Pharm Res. 2007 Nov;30(11):1368-73. DOI:10.1007/BF02977358