Phosalone

Pure product is white crystal with garlic odor. m.p. 48℃, small volatility, saturation concentration in air less than 0.01mg/m3(24℃),about 0.02mg/m3(40℃),about 0.1mg/m3(50℃),about 0.3mg/m3(60℃). Freely soluble in acetone, acetonitrile, acetophenone, benzene, chloroform, cyclohexanone, dioxane, ethyl acetate, dichloroethane, methyl ethyl ketone, toluene, xylene and other organic solvents; soluble in methanol, ethanol, solubility about 20%; insoluble in water, solubility about 0.1%. Stable in nature, no obvious failure when stored at room temperature for 2 years or at 50℃ for 30d, no corrosiveness.

Insecticide; acaracide

Phosalone is used to control codling moth, aphids, beetles and thrips on fruit trees

Insecticide, acaricide.

Phosalone is a organophosphate compouund used as insecticide and acaricide. Phosalone is a weak inhibitor of acetylcholinesterase.

ChEBI: A member of the class of 1,3-benzoxazoles carrying a [(diethoxyphosphorothioyl)sulfanyl]methyl group at the nitrogen atom, an oxo group at position 2 and a chloro group at position 6. It is an organothiophosphate insecticide.

Poison by ingestion, skin contact,and possibly other routes. A cholinesterase inhibitor. Seealso PARATHION. When heated to decomposition itemits very toxic fumes of Cl^-, NOx, POx, and SOx.

Plant. Degrades in plants to chlorbenzoxazolone, formaldehyde and diethyl phosphorodithioate (Hartley and Kidd, 1987)
Soil. Ambrosi et al. (1977a) studied the persistence and metabolism of phosalone in both moist and flooded Matapeake loam and Monmouth fine sandy loam. Phosalone rapidly degraded (half-life 3 to 7 days) but mineralization to carbon dioxide accoun
Chemical/Physical. Emits toxic fumes of chlorine, phosphorus, nitrogen and sulfur oxides when heated to decomposition (Sax and Lewis, 1987)

Photodegradation of phosalone in solvent yields dechlorinated phosalone. Irradiation in methanol affords O,O-diethyl-S-methylphosphorothioate and 6- chloro-3-methoxymethyl-2-oxobenzoxazoline with other common products. Photolysis of phosalone in the solid state as a thin film on a glass surface produces a number of photoproducts including 6-chloro-3- mercaptomethyl-2-oxobenzoxazoline and its dimeric disulfide.

Orally administered phosalone in mammals is rapidly degraded by oxidation and hydrolysis to give O,O-diethyl hydrogen phosphorothioate and phosphorodithioate and 6-chloro-2,3-dihydro-2-oxobenzoxazole, which is further metabolized and excreted in the urine. It is strongly adsorbed to soil and rapidly degraded with DT₅₀ values of 1–4 d.

Phosalone is hydrolysed by strong acids and alkalis with a DT₅₀, of 9 days at pH 9 (PM).