1,1-O-(4,6-Dihydroxy-1,2-phenylenemethylene)-4-O-[6-O-(1-oxo-2,4-decadienyl)-β-D-galactopyranosyl]-α-D-glucopyranose 3-(7-hydroxy-8,14-dimethylhexadeca-2,4,8,10-tetraenoate)

Papulacandins A is an antibiotic. Papulacandins A can be found in the fungus Papularia sphaerosperma. Papulacandins A has strong anti-yeast effect, but has no effect on filamentous fungi, bacteria and protozoa[1][2].

ChEBI: A papulacandin substituted by a (2E,4E)-deca-2,4-dienoyl chain at the O-(6') position and a (2E,4E,7S,8E,10E,14<stereo S)-7-hydroxy-8,14-dimethylhexadeca-2,4,8,10-tetraenoyl chain at the O-(3) position. It is a carbohydrate-containing antibiotic from the deuteromycetous fungus Papularia sphaerosperma which shows potent antifungal ac ivity against Candida albicans.

[1] Traxler P, et al. Papulacandins, a new family of antibiotics with antifungal activity. Structures of papulacandins A, B, C and D. J Antibiot (Tokyo). 1980 Sep;33(9):967-78. DOI:10.7164/antibiotics.33.967
[2] Stanislas C, et al. C-Glycosides. 9. Stereospecific Synthesis of C-Glycosidic Spiroketal of the Papulacandins. J. Org. Chem. 1991 Dec;56:6289-6292.