(S)-Trichostatin A ((S)-TSA) is a HDAC6-selective inhibitor with IC50s of 9.88 nM and 11.1 nM for Zebrafish HDAC6 and Human HDAC6, respectively. (S)-Trichostatin A weakly inhibits other human HDACs[1].
hHDAC6: 11.1 nM (IC50); Zebrafish HDAC6: 9.88 nM (IC50); hHDAC1: 206.3 nM (IC50); hHDAC2: 612.65 nM (IC50); hHDAC3: 320.8 nM (IC50); hHDAC4: 6341 nM (IC50); hHDAC5: 6325 nM (IC50); hHDAC7: 1823.5 nM (IC50); hHDAC8: 312.2 nM (IC50); hHDAC9: 4824 nM (IC50); hHDAC10: 403.35 nM (IC50); hHDAC11: 2684 nM (IC50)
