2,4-Difluoronitrobenzene (15 ) was dissolved in anhydrous ethanol (10 mL) in a Schlenk flask.
mmol) was dissolved in anhydrous ethanol (10 mL) in a Schlenk flask, 25% ammonia solution (10 ) was added to the mixture, and the reaction mixture was stirred at room ambient temperature.
mL), the reaction mixture was stirred at room temperature, and the progress of the reaction was detected by TLC spot plate; after the reaction was finished, the precipitate was filtered off by diatomaceous earth, washed with water, and the precipitate was dried in air to obtain the target product 5-fluoro-2-nitroaniline.
