SeMilicoisoflavone B

It is a natural product derived from plant source th at finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

ChEBI: A member of the class of 7-hydroxyisoflavones that is 2',2'-dimethyl-2'H,4H-3,6'-bichromen-4-one substituted by hydroxy groups at positions 5, 7 and 8'. It has been isolated from Glycyrrhiza uralensis.

Semilicoisoflavone B:

• Suppresses proinflammatory cytokine production, downregulates TLR4 expression, and diminishes reactive oxygen species generation in vitro.
• Inhibits the growth and division of cancer cells by triggering apoptosis and arresting the cell cycle, offering potential for effective tumor therapy.
• Restricts Caco-2 cell proliferation, suggesting potential for metabolic syndrome therapy.