Acyl-CoA oxidase (ACO) catalyses the first and rate-determining step of the peroxisomal beta-oxidation of fatty acids and a major producer of hydrogen peroxide (H2O2)[1].
References
[1] Arent S, et, al. Structure and function of plant acyl-CoA oxidases. Plant Physiol Biochem. 2008 Mar;46(3):292-301. DOI:10.1016/j.plaphy.2007.12.014