Pentanoic acid, 5-[[2-(acetylamino)-3,4,6-tri-O-benzoyl-2-deoxy-β-D-galactopyranosyl]oxy]-

TriGalNAc CBz is a GalNAc derivative and tri-GalNAc is an asialoglycoprotein receptor (ASGPR) ligand. TriGalNAc CBz can be used for mRNA drug delivery as well as lysosomal targeted chimerism (LYTAC) studies[1].

[1] Kallanthottathil G. Rajeev, et al. Compositions and methods for targeted rna delivery. WO2021178725.
[2] Biessen EA, Sliedregt-Bol K, 'T Hoen PA, et al. Design of a targeted peptide nucleic acid prodrug to inhibit hepatic human microsomal triglyceride transfer protein expression in hepatocytes. Bioconjug Chem. 2002;13(2):295-302. DOI:10.1021/bc015550g
[3] Ahn G, et al. LYTACs that engage the asialoglycoprotein receptor for targeted protein degradation[J]. Nature Chemical Biology, 2021, 17(9): 937-946.