[2S-[2R[R(R*)]]]-N-[2-[4-(aminocarbonyl)-3-thiazolidinyl]-1-(1H-imidazol-4-ylmethyl)-2-oxoethyl]-6-oxopiperidine-2-carboxamide

Usage And Synthesis

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Animal Model:	20-30 g, male MF1 mice^[1]
Dosage:	5 mg/kg
Administration:	I.p.
Result:	Induced blinking and forepaw licking in both acutely isolated and paired mice.

Animal Model:	20-30 g, male MF1 mice^[1]
Dosage:	0.25-60 mg/kg
Administration:	I.p.
Result:	Induced blinking was bell-shaped with an ED₅₀ value of 1.72 mg/kg.

Animal Model:	25-30 g, Male Swiss-Webster mice^[2]
Dosage:	10 ng-10 μg/mouse
Administration:	I.c.v.
Result:	Produced a hyperthermic response for 4 h followed by a return to normal temperature.