KRAS inhibitor-26 (compound 194a) is a potent KRAS G12V inhibitor (IC50: ≤100 nM). KRAS inhibitor-26 can be used for cancer research[1].
KRas G12V: <100 nM (IC50)
[1] James Paul LAJINESS, et al. Pyridopyrimidine kras inhibitors. Patent. WO 2024/040131 A1.