Sootepin D

Sootepin D (compound 6), a triterpene from the apical bud of Gardenia sootepensis, inhibits TNF-α-induced NF-κB activity with an IC50 of 8.3μM. Sootepin D has anti-inflammatory activity[1].

NF-κB

[1] Youn UJ, et al. Anti-inflammatory triterpenes from the apical bud of Gardenia sootepensis.Fitoterapia. 2016 Oct;114:92-97. DOI:10.1016/j.fitote.2016.08.012