BNC-1 is a novel modulator of amyloid pathology. BNC-1 significantly decreases amyloid burden and improves markers of synaptic integrity in well-established mouse models of amyloid deposition by promoting phosphorylation and activation of Elk-1.
Uses
BNC-1 is an Elk-1 activator that can promote phosphorylation and activation of Elk-1[1].
References
[1] Mark A Lovell, et al. A Novel Small Molecule Modulator of Amyloid Pathology. J Alzheimers Dis. 2016 May 4;53(1):273-87. DOI:10.3233/JAD-151160
