| Name | β-Aminopropionitrile hydrochloride |
| Description | β-Aminopropionitrile hydrochloride is a selective, orally available, irreversible inhibitor of lysyl oxidase (LOX) that reduces metastatic seeding potential in MDA-MB-231 breast cancer cells. |
| In vitro | In an in vitro model of insulin resistance, β-Aminopropionitrile hydrochloride can restore the expression of GLUT4 and adiponectin to normal levels and improve Vitis vinifera sugar uptake [1].
β-Aminopropionitrile hydrochloride (500 μM, 72 hours) can block hypoxia-induced epithelial-mesenchymal transition (EMT) morphological changes and marker protein alterations in cervical squamous cell carcinoma cells, while also inhibiting their invasion and migration capabilities (in vitro experiment) [2]. |
| In vivo | β-Aminopropionitrile hydrochloride, at a dose of 100 mg/kg/day administered orally for 6 weeks, reduced weight gain and improved metabolic profiles in diet-induced obese rats [1].
β-Aminopropionitrile hydrochloride, at a dose of 1 g/kg/day administered orally for 4 weeks, induced thoracic aortic dissection in C57BL/6 mice [3]. |
| Storage | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | β-Aminopropionitrile Hydrochloride | beta-Aminopropionitrile Hydrochloride | BAPN Hydrochloride | b-Aminopropionitrile Hydrochloride |
| Inhibitors Related | Sucrose | Aceglutamide | Nicotinamide riboside malate | DL-Lysine | D(+)-Raffinose pentahydrate | Guanidine hydrochloride | Malic acid | Formamide | Glycerol | Thymidine | Corn starch | Gluconate Calcium |
| Related Compound Libraries | Ferroptosis Compound Library | Bioactive Compound Library | Neuronal Signaling Compound Library | Lipid Metabolism Compound Library | Bioactive Compounds Library Max | Human Metabolite Library |
United States
