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ChemicalBook Product Catalog API Antineoplastic agents Natural sources of antineoplastic DEMECOLCINE

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DEMECOLCINE NEW

$1.00 100KG

$5.00 25KG

$8.00 1KG

Min. Order1KG
Purity99%
Cas No477-30-5
Supply Abilityg-kg-tons, free sample is available
Update time2025-09-25

Henan Fengda Chemical Co., Ltd

VIP3Y

China

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Chemical Properties

Product Name	DEMECOLCINE
CAS No	477-30-5
EC-No
Min. Order	1KG
Purity	99%
Supply Ability	g-kg-tons, free sample is available
Release date	2025/09/25

1. Materials information

Names

Name	(-)-demecolcine
Synonym	More Synonyms

(-)-Demecolcine Biological Activity

Description	Colcemid (Demecolcine), a derivative of colchicine, is a potent mitotic inhibitor[1][2]. Colcemid binds to the protein tubulin and arrest cells in metaphase for karyotyping assays. Colcemid incuces cell apoptosis and can be used for cancer research[2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin Research Areas >> Inflammation/Immunology Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin
References	[1]. T Tsuchida, et al. Colcemid-induced apoptosis of cultured human glioma: electron microscopic and confocal laser microscopic observation of cells sorted in different phases of cell cycle. Cytometry. 1998 Apr 1;31(4):295-9. [2]. Ashley M Rozario, et al. Ultra-Low Colcemid Doses Induce Microtubule Dysfunction as Revealed by Super-Resolution Microscopy. Bioexiv.

Description

Colcemid (Demecolcine), a derivative of colchicine, is a potent mitotic inhibitor[1][2]. Colcemid binds to the protein tubulin and arrest cells in metaphase for karyotyping assays. Colcemid incuces cell apoptosis and can be used for cancer research[2].

Related Catalog

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin

References

[1]. T Tsuchida, et al. Colcemid-induced apoptosis of cultured human glioma: electron microscopic and confocal laser microscopic observation of cells sorted in different phases of cell cycle. Cytometry. 1998 Apr 1;31(4):295-9.

[2]. Ashley M Rozario, et al. Ultra-Low Colcemid Doses Induce Microtubule Dysfunction as Revealed by Super-Resolution Microscopy. Bioexiv.

Chemical & Physical Properties

Density	1.2±0.1 g/cm3
Boiling Point	625.5±55.0 °C at 760 mmHg
Melting Point	73-75ºC
Molecular Formula	C₂₁H₂₅NO₅
Molecular Weight	371.427
Flash Point	332.1±31.5 °C
Exact Mass	371.173279
PSA	66.02000
LogP	1.52
Vapour Pressure	0.0±1.8 mmHg at 25°C
Index of Refraction	1.582

2. Packaging of materials

For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.

Or smaller package 1kg/bottle, 10kgs/bottle as request.

3. Shipping & Delivery

By Express

Provide door to door service

Suitable for goods under 50kg

Delivery: 3-7 days

Cost: low cost

By Air

Provide airport to airport service

Suitable for goods over 50kg

Delivery: 3-14 days

Cost: high cost

By Sea

Provide seaport to seaport service

Suitable for goods over 100kg

Delivery: 2-45 days

Cost: low cost

4. Contact information

For more details, pls contact us freely.

Email address: sun@fdachem.com

Mob: 86 13526505137

WhatsApp/Skype/Wechat/LINE: 8613526505137

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Company Profile Introduction

Henan Fengda Chemical Co., Ltd. a research customization and supplier specializing in PPb grade ultra-high purity electronic chemicals, deeply rooted in the semiconductor and new display fields, committed to providing the most core and purest chemical components for photoresist and high-end display materials. We provide key monomers for KrF/ArF photoresist, photoacid generators (PAGs), photoacids, and etching solution raw materials, providing cornerstone materials for advanced process photoresist formulations; We take ICP-MS full spectrum metal impurity analysis as the quality cornerstone and provide ICP-MS metal impurity COA reports to meet the strict industry requirements for PPb grade electronic chemical materials. The COA report contains important data such as NA, Mg, K, Ca, Al, Cr, Fe, Ni, Cu, Zn, Pb, Ag, etc. To provide customers with pure and reliable source assurance for cutting-edge research and stable production.