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ChemicalBook Product Catalog Analytical Chemistry Standard Forensic and veterinary standards Retigabine

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Retigabine NEW

$0.10 1000KG

$5.00 1KG

Min. Order1KG
Purity99%
Cas No150812-12-7
Supply Abilityg-kg-tons, free sample is available
Update time2025-09-25

Henan Fengda Chemical Co., Ltd

VIP3Y

China

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Chemical Properties

Product Name	Retigabine
CAS No	150812-12-7
EC-No
Min. Order	1KG
Purity	99%
Supply Ability	g-kg-tons, free sample is available
Release date	2025/09/25

1. Materials information

Names

Name	ezogabine
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	430.0±45.0 °C at 760 mmHg
Molecular Formula	C16H18FN3O2
Molecular Weight	303.331
Flash Point	213.9±28.7 °C
Exact Mass	303.138306
PSA	76.38000
LogP	0.81
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.656
Storage condition	room temp

MSDS

Retigabine MSDS(Chinese)

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H319-H413
Precautionary Statements	P305 + P351 + P338
Hazard Codes	T,N,Xn,F,Xi
Risk Phrases	23-25-50/53-36-20/21/22-11
Safety Phrases	45-60-61-36/37-16-26
RIDADR	NONH for all modes of transport

Synthetic Route

Previous 1/4 Next

Ethyl {4-[(4-fl...

150812-23-0

~87%

Retigabine

150812-12-7

Literature: GLAXO GROUP LIMITED; FITZGERALD, Russ, N; MILLAR, Alan; TOCZKO, Jennifer, Fell Patent: WO2012/98075 A1, 2012 ; Location in patent: Page/Page column 8 ;

benzyl (4-((eth...

1449372-53-5

~90%

Retigabine

150812-12-7

Literature: OLON S.P.A.; LONGONI, Davide; FRIGOLI, Samuele; ALPEGIANI, Marco Patent: WO2013/114315 A1, 2013 ; Location in patent: Page/Page column 9 ;

2-ethoxycarbony...

1314406-56-8

~62%

Retigabine

150812-12-7

Literature: ARCH PHARMALABS LIMITED; MANDAL, Arun Kanti; RANBHAN, Kamlesh Jayantilal; SAXENA, Sudhanshu; GAIKWAD, Sanjay Ramrao; SARJEKAR, Pushpalata Balkrishna Patent: WO2013/11518 A1, 2013 ; Location in patent: Page/Page column 47-48 ;

Articles18

Enhanced in vitro CA1 network activity in a sodium channel β1(C121W) subunit model of genetic epilepsy.

Epilepsia 55(4) , 601-8, (2014)

A NaV β1(C121W) mouse model of human genetic epilepsy has enhanced neuronal excitability and temperature sensitivity attributed to a decreased threshold for action potential firing in the axon initial...

Safety profile of two novel antiepileptic agents approved for the treatment of refractory partial seizures: ezogabine (retigabine) and perampanel.

Expert Opin. Drug Saf. 12(6) , 847-55, (2013)

Complex-partial seizures are frequently resistant to antiepileptic therapy. Two new medications with mechanisms of action novel within the antiepileptic class have recently received approval for the a...

Ezogabine (retigabine) and its role in the treatment of partial-onset seizures: a review.

Clin. Ther. 34(9) , 1845-56.e1, (2012)

Ezogabine, also known as retigabine, is a recently approved anticonvulsant medication with a novel mechanism of action. It activates low-threshold voltage-gated potassium channels, leading to hyperpol...

Synonyms

N-(2-amino-4-(4-fluorobenzylamino)-phenyl)carbamic acid ethylester

Retigabine

Carbamic acid, N-[2-amino-4-[[(4-fluorophenyl)methyl]amino]phenyl]-, ethyl ester

Trobalt

[2-Amino-4-(4-fluoro-benzylamino)-phenyl]-carbamic acid ethyl ester

2-Amino-4-(4-fluorbenzylamino)-1-ethoxycarbonylaminobenzene

N-(2-amino-4-(4-fluorobenzylamino)phenyl)carbamic acid ethyl ester

Ethyl (2-amino-4-(((4-fluorophenyl)methyl)amino)phenyl)carbamate

Ezogabine

D-23129, Ezogabine, N-(2-Amino-4-(4-fluorobenzylamino)phenyl)carbamic acid ethyl ester

Ethyl {2-amino-4-[(4-fluorobenzyl)amino]phenyl}carbamate

Potiga

EINECS 200-835-2

2. Packaging of materials

For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.

Or smaller package 1kg/bottle, 10kgs/bottle as request.

3. Shipping & Delivery

By Express

Provide door to door service

Suitable for goods under 50kg

Delivery: 3-7 days

Cost: low cost

By Air

Provide airport to airport service

Suitable for goods over 50kg

Delivery: 3-14 days

Cost: high cost

By Sea

Provide seaport to seaport service

Suitable for goods over 100kg

Delivery: 2-45 days

Cost: low cost

4. Contact information

For more details, pls contact us freely.

Email address: Tina@fdachem.com

Mob: 86 13213167925

WhatsApp/Skype/Wechat/LINE: 86 13213167925

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Company Profile Introduction

Henan Fengda Chemical Co., Ltd. a research customization and supplier specializing in PPb grade ultra-high purity electronic chemicals, deeply rooted in the semiconductor and new display fields, committed to providing the most core and purest chemical components for photoresist and high-end display materials. We provide key monomers for KrF/ArF photoresist, photoacid generators (PAGs), photoacids, and etching solution raw materials, providing cornerstone materials for advanced process photoresist formulations; We take ICP-MS full spectrum metal impurity analysis as the quality cornerstone and provide ICP-MS metal impurity COA reports to meet the strict industry requirements for PPb grade electronic chemical materials. The COA report contains important data such as NA, Mg, K, Ca, Al, Cr, Fe, Ni, Cu, Zn, Pb, Ag, etc. To provide customers with pure and reliable source assurance for cutting-edge research and stable production.