1-Boc-azetidine-3-carboxylic acid NEW

$2.20 100kg

$6.60 50kg

$8.80 1kg

Min. Order1kg
Purity99%
Cas No142253-55-2
Supply Ability100kg
Update time2026-04-17

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

VIP1Y

China

Chemical Properties

Product Name	1-Boc-azetidine-3-carboxylic acid
CAS No	142253-55-2
EC-No
Min. Order	1kg
Purity	99%
Supply Ability	100kg
Release date	2026/04/17

1-Boc-azetidine-3-carboxylic acid

Modify Date: 2024-01-02 20:16:02

1-Boc-azetidine-3-carboxylic acid structure	Common Name	1-Boc-azetidine-3-carboxylic acid
	CAS Number	142253-55-2	Molecular Weight	201.220
	Density	1.2±0.1 g/cm3	Boiling Point	321.0±35.0 °C at 760 mmHg
	Molecular Formula	C9H15NO4	Melting Point	100.1-101.9°C
	MSDS	ChineseUSA	Flash Point	147.9±25.9 °C

Purity		Quantity		Budget		Inquiry

Use of 1-Boc-azetidine-3-carboxylic acid

1-Boc-azetidine-3-carboxylic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 1-Boc-azetidine-3-carboxylic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1][2]

Properties

Name	1-Boc-3-Azetidine-3-carboxylic acid
Synonym	More Synonyms

Description	1-Boc-azetidine-3-carboxylic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 1-Boc-azetidine-3-carboxylic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1][2]
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker Signaling Pathways >> PROTAC >> PROTAC Linker
Target	Non-cleavable
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].
References	[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337. [2]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

Density	1.2±0.1 g/cm3
Boiling Point	321.0±35.0 °C at 760 mmHg
Melting Point	100.1-101.9°C
Molecular Formula	C9H15NO4
Molecular Weight	201.220
Flash Point	147.9±25.9 °C
Exact Mass	201.100113
PSA	66.84000
LogP	0.27
Vapour Pressure	0.0±1.5 mmHg at 25°C
Index of Refraction	1.510
Storage condition	Store at -15°C

1-Boc-azetidine-3-carboxylic acid MSDS(Chinese)

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi: Irritant;
Risk Phrases	36/37/38
Safety Phrases	S22-S24/25-S37-S26
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2933990090

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