| Name | 1-Octanol |
| Description | 1-Octanol, a saturated fatty alcohol, functions as an inhibitor of T-type calcium channels (T-channels), showing an inhibitory concentration (IC50) of 4 μM for native T-currents[1]. Additionally, 1-Octanol is recognized for its potential as a biofuel, possessing diesel-like properties[2]. |
| In vitro | 1-octanol inhibits native T-currents at subanesthetic concentrations with an IC50 of approximately 4 μM, yet it is up to 30-fold less potent in inhibiting recombinant CaV3.3 T-channels heterologously expressed in human embryonic kidney cells [1]. |
| Storage | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 50 mg/mL (383.94 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (15.36 mM), Sonication is recommended.
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| Keywords | T-type calcium channel | T-currents | T-channels | saturated | Human Endogenous Metabolite | EndogenousMetabolite | Endogenous Metabolite | diesel-like | CalciumChannel | Calcium Channel | biofuel | alcohol | 1-Octanol | 1Octanol | 1 Octanol |
| Inhibitors Related | Sucrose | Aceglutamide | Nicotinamide riboside malate | 2,4,6-Tri-tert-butylphenol | D(+)-Raffinose pentahydrate | Guanidine hydrochloride | Formamide | Glycerol | Thymidine | Corn starch | Hyaluronic acid sodium (MW 20 kDa) | Gluconate Calcium |
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