L-Alanyl-L-Glutamine NEW

Specification

Welcome to contact us to get complete COA.

 What is L-Alanyl-L-Glutamine?

L-Alanyl-L-Glutamine (often abbreviated as Ala-Gln) is a stable, water-soluble dipeptide. It is composed of two amino acids linked together: L-Alanine and L-Glutamine.

It is primarily used in a clinical setting as a component of parenteral nutrition (PN), which is a method of feeding that bypasses the gastrointestinal tract, delivering nutrients directly into the bloodstream.

The core reason for its existence is a practical problem: Glutamine, on its own, is highly unstable in solution and has poor water solubility, making it unsuitable for intravenous infusions. By bonding it with L-Alanine, it becomes a stable and soluble compound that can be safely administered through an IV. Once in the body, it is rapidly broken down (hydrolyzed) to release its constituent amino acids, L-Glutamine and L-Alanine, for the body to use.

 Key Benefits and "Selling Points"

L-Alanyl-L-Glutamine is specifically indicated for patients in a catabolic or high-metabolic state, such as those who are critically ill, have suffered major trauma, or have undergone extensive surgery. In these conditions, the body's demand for glutamine far exceeds its ability to produce it, making glutamine a "conditionally essential" amino acid.

Here are the primary benefits that make it a crucial component of nutritional support for these patients:

1. Maintains Gut Barrier Integrity

Glutamine is the primary fuel source for the cells lining the small intestine (enterocytes). During severe illness or stress, the gut lining can become damaged, leading to "leaky gut," where bacteria and toxins can pass from the intestine into the bloodstream. Supplementing with L-Alanyl-L-Glutamine helps to:

Preserve the structure and function of the intestinal mucosal barrier.

Prevent bacterial translocation, which can lead to severe infections and sepsis.

2. Enhances Immune Function

Glutamine is often called the "fuel for the immune system". Immune cells, such as lymphocytes and macrophages, rely heavily on glutamine to function effectively, especially when the body is under stress. L-Alanyl-L-Glutamine supplementation helps to:

Support the proliferation and activity of immune cells.

Improve the body's overall immune response during critical illness, potentially reducing the risk of infections.

3. Improves Nitrogen Balance & Protein Metabolism

A catabolic state is characterized by the excessive breakdown of muscle tissue to provide energy and amino acids for vital functions. This leads to a negative nitrogen balance and muscle wasting. L-Alanyl-L-Glutamine helps to counteract this by:

Promoting protein synthesis and reducing muscle breakdown.

Improving the body's nitrogen balance, which is a key indicator of nutritional status and recovery.

4. Safe and Effective Delivery of Glutamine

This is the fundamental "selling point" of the dipeptide form itself. It solves the delivery problem of pure glutamine.

Stability & Solubility: It is highly stable and water-soluble, making it ideal for intravenous formulations.

Bioavailability: It is efficiently taken up by the body and rapidly hydrolyzed to release free glutamine and alanine where they are needed.

Package

Shipping 

Company informations

Contact information