2-Adamantanone Cas 700-58-3
Product Description
Product Name: 2-Adamantanone
Synonyms: Adamantan-2-one
CAS No. 700-58-3
M.F.: C10H14O
M.W.: 150.22
EINECS: 211-847-2
Specifications
Items | Specifications | Results |
Appearance | Off-white to white solid | Conforms |
Purity | ≥98.0% | 99.6% |
Water | ≤0.5% | 0.1% |
Conclusion | The product conforms to the above specifications. |
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2-Adamantanone is an organic compound with the molecular formula C₁₀H₁₄O. It is a ketone derivative of adamantane, where a carbonyl group (C=O) is attached to the bridgehead carbon at position 2 of the adamantane cage.
Structure: Imagine the rigid, three-dimensional, diamond-like cage structure of adamantane (a cycloalkane with 10 carbon atoms). 2-Adamantanone is formed by replacing one of the hydrogen atoms on a specific carbon (the "bridgehead") with an oxygen atom, creating a ketone functional group.
Key Properties:
White crystalline solid at room temperature.
Possesses the high chemical and thermal stability characteristic of the adamantane skeleton.
The carbonyl group makes it a versatile intermediate for chemical synthesis, as it can undergo various reactions (reductions, Grignard reactions, etc.) to introduce other functional groups onto the robust adamantine core.
Primary Uses and Applications
2-Adamantanone's main value lies not in direct application, but as a crucial building block (synthon) in organic and medicinal chemistry. Its rigid, lipophilic (fat-soluble) structure is highly desirable for designing pharmaceutical agents.
1. Pharmaceutical Intermediates (Most Significant Use)
It is a key precursor in the synthesis of several important drugs and bioactive molecules. The adamantane moiety often enhances lipid solubility, metabolic stability, and binding affinity to biological targets.
Adapalene: A topical retinoid used to treat acne. 2-Adamantanone is a starting material in its synthesis.
Saxagliptin: A dipeptidyl peptidase-4 (DPP-4) inhibitor used for type 2 diabetes.
Antiviral Agents: Derivatives of adamantane, such as amantadine and rimantadine (used against influenza A), share the same core structure. While not made directly from the ketone, 2-adamantanone is used to create novel analogs and more complex derivatives with potential antiviral, antibacterial, or neuroprotective activity.
Other Drug Candidates: It serves as a scaffold for developing potential treatments for neurological disorders (e.g., Parkinson's, Alzheimer's) and various other conditions.
2. Material Science & Polymer Chemistry
High-Performance Polymers: Incorporated into polymer backbones to create materials with enhanced thermal stability, rigidity, and solubility. These polymers are investigated for use in advanced coatings, membranes, and engineering plastics.
Dendrimers and Nanostructures: Its symmetrical, polycyclic structure makes it a useful core for building complex dendritic molecules.
3. Organic Synthesis & Research
Model Compound: Used in physical organic chemistry studies to investigate steric effects and reaction mechanisms due to its unique, rigid geometry.
Ligand and Catalyst Design: Functionalized to create bulky ligands for metal catalysts or as a core for molecular recognition.
4. Analytical Chemistry
Summary
| Aspect | Description |
|---|
| What it is | A ketone-functionalized derivative of the stable adamantane cage. |
| Direct Uses | Very limited as an end-product. |
| Primary Value | A versatile chemical intermediate or building block. |
| Major Application | Synthesis of pharmaceuticals (e.g., Adapalene, Saxagliptin) and drug candidates. |
| Key Feature | Provides a rigid, stable, and lipophilic 3D scaffold that improves drug properties. |
In essence, 2-Adamantanone is a workhorse molecule in the chemist's toolkit, prized for its ability to efficiently introduce the valuable adamantane structure into more complex, high-value molecules, especially in the pharmaceutical industry.
Packing & Shipping
FAQ
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3. How should I pay?
We accept various payment terms such as L/C,T/T, Western Union and Money Gram.
4. Is there a discount?
Different quantity has different discount.
5.What's your MOQ?
Different products have different MOQ, such as:
1).Peptide products, the MOQ is 1 gram level
2).Liquid products, the MOQ is usually 50-100ML
3).API, the MOQ is 1KG
4).Intermediate products and conventional product, the MOQ is 1KG; custom-tailored products, the MOQ depends on the production process.
5).Food additives and vitamin, the MOQ is usually one package: such as Vitamin C is 25KG / drum, Vitamin E oil or Vitamin A oil is 5KG/bag;Vitamin E powder or Vitamin A powder is 20KG / cartons.
6).Agrochemical , the MOQ is 1KG, except preparations.
6.How do we take the quality complaint ?
First of all, our quality control will reduce the quality issue to near zero. If there is a quality problem caused by us, we will send you free goods for replacement or compensate your loss.
Company Information
Company profile
Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/Feed additives, Fine chemicals in distributing the products of our own company and affiliated enterprises, are the members of Hubei E-commerce Chamber.
Our company has professional persons who major in chemical R&D and sicentific management, supply fine chemical products with high quality and close service, also supply custom-tailored products according to our clients’ requirement.
We have a positive and self-motivated management work team with a common philosophy, caring and commitment through teamwork, our team strive to achieve success in delighting our clients and ourselves.
Since Wuhan Fortuna Chemical Co., Ltd founded, we continuously innovate our products and improve our service, sales network. Hence, we initiate the first sale mode on net in China, which is the retail trade of small package bring along wholesale of diversified management modes. Our products are exported widely to South Korea, Vietnam, Australia, Europe and South America, highly recommended by our clients.
We insist on the management creed “Market is our compass, Quality is our life, Credit is our soul”. Clients’ trust is our forward powder, their satisfaction is our struggling goal.
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