Chinese name: 3-fluoro-pyridine-4-boric acid - Pinar ester
English name: 3-Fluoropyridine-4-boronic acid pinacol ester
CAS: 458532-88-2
Chemical formula: C11H15BFNO2
Molecular weight: 223.05
InChI: InChI = 1 / C11H15BFNO2 / c1-10 (2) (3, 4) 11-12 of 16 (15-10) 8-5-6-8-5-6 (8) 13 / h5-7 h, 1-4 h3
Density: 1.09± 0.1g /cm3(Predicted)
Melting point: 125-127°C
Boiling point: 292.4±25.0 °C(Predicted)
Flash point: 130.7°C
Vapor pressure: 0.00321mmHg at 25°C
Refractive index: 1.477
Acidity coefficient: 1.97±0.20(Predicted)
Storage conditions: under inert gas (nitrogen or Argon) at 2-8°C
MDL number: MFCD06798251
Nature:
- Appearance: Colorless or light yellow solid
Purpose:
3-fluoropyridine-4-borate-Pinate is an intermediate used in organic synthesis chemistry. The substance can also be used in cross-coupling reactions in organic synthesis reactions, such as phenyl modification reactions, olefin synthesis, etc.
Preparation:
There are various methods for the preparation of 3-fluoropyridine 4-borate-Pinacyl ester, and one common one is the reaction of 3-fluoropyridine with borate (such as pinacol ether) under acidic conditions.