| Name | 3-O-Methylgalangin |
| Description | 3-O-Methylgalangin (GALANGIN-3-METHYLETHER) has antibacterial activity, it has inhibitory effects on Pseudomonas aeruginosa. GALANGIN-3-METHYLETHER has hypolipidemic activity, the action is due to the inhibition of pancreatic lipase. |
| Cell Research | L. amazonensis amastigotes were maintained and cultured axenically .Washed parasites were resuspended in RPMI-1640 medium supplemented with 4% fetal calf serum, pH 5.0, and incubated at 33 C for 18 h with crude extracts (1 mg/mL) or isolated compounds(GALANGIN-3-METHYLETHER) (0.014, 0.084, 0.5, and 1.0 mg/mL) dissolved in dimethyl sulfoxide (DMSO)/RPMI-1640 (1:99).?The amastigote viability was assessed colorimetrically by the reduction of a tetrazolium salt (MTT) as.?Absorbances were expressed as percentages relative to untreated controls.?Amphotericin B (0.02 mg/mL) was used as the positive control and DMSO/RPMI-1640 (1:99) as negative control.?The bioassays were carried out in triplicate. |
| In vitro | GALANGIN-3-METHYLETHER markedly reduced the viability of Leishmania amastigotes. |
| Storage | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 25 mg/mL (87.95 mM), Sonication is recommended.
10% DMSO+90% Corn Oil : 1 mg/mL (3.52 mM), Sonication is recommended.
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| Keywords | Inhibitor | inhibit | Galangin 3-methyl ether | Bacterial | 3-O-Methylgalangin | 3OMethylgalangin | 3 O Methylgalangin |
| Inhibitors Related | Neomycin sulfate | Adipic dihydrazide | Levulinic acid | D(+)-Raffinose pentahydrate | Sulfamethoxazole sodium | Terbinafine hydrochloride | Doxycycline | Hyaluronic acid sodium (MW 20 kDa) | Dimethyl sulfoxide | Sodium diacetate | Sodium bicarbonate | BES |
| Related Compound Libraries | Polyphenolic Natural Product Library | Flavonoid Natural Product Library | Traditional Chinese Medicine Monomer Library | Bioactive Compound Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Natural Product Library | Inhibitor Library | Natural Product Library for HTS | Anti-infective Natural Product Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Food as Medicine Compound Library |
United States
