4-Aminoantipyrine
Modify Date: 2024-01-02 16:21:27
 4-Aminoantipyrine structure | Common Name | 4-Aminoantipyrine |
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| CAS Number | 83-07-8 | Molecular Weight | 203.240 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 309.0±45.0 °C at 760 mmHg |
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| Molecular Formula | C11H13N3O | Melting Point | 105-110 °C(lit.) |
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| MSDS | ChineseUSA | Flash Point | 140.7±28.7 °C |
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| Symbol | 
GHS07 | Signal Word | Warning |
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Use of 4-Aminoantipyrine
Ampyrone is a reagent for glucose determination in the presence of peroxidase and phenol. |
Properties
Articles46
Spectrum
Names
| Name | 4-aminoantipyrine |
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| Synonym | More Synonyms |
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4-Aminoantipyrine Biological Activity
| Description | Ampyrone is a reagent for glucose determination in the presence of peroxidase and phenol. |
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| Related Catalog | Research Areas >> Others |
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| Target | COX |
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| References | [1]. Berno CR, et al. 4-Aminoantipyrine reduces toxic and genotoxic effects of doxorubicin, cisplatin, and cyclophosphamide in male mice. Mutat Res Genet Toxicol Environ Mutagen. 2016 Jul;805:19-24. |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 309.0±45.0 °C at 760 mmHg |
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| Melting Point | 105-110 °C(lit.) |
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| Molecular Formula | C11H13N3O |
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| Molecular Weight | 203.240 |
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| Flash Point | 140.7±28.7 °C |
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| Exact Mass | 203.105865 |
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| PSA | 52.95000 |
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| LogP | -0.40 |
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| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
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| Index of Refraction | 1.607 |
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| Storage condition | Store at RT. |
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| Stability | Stable. May be light sensitive. |
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| Water Solubility | ca. 500 g/L (20 ºC) |
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MSDS
4-Aminoantipyrine MSDS(Chinese) |
Toxicological Information
CHEMICAL IDENTIFICATIONCHEMICAL NAME : Antipyrine, 4-amino-
CAS REGISTRY NUMBER : 83-07-8
MOLECULAR FORMULA : C11-H13-N3-O
HEALTH HAZARD DATAACUTE TOXICITY DATASPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 1700 mg/kg
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 1200 mg/kg
SPECIES OBSERVED : Rodent - mouse
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
MUTATION DATADOSE/DURATION : 312 ug/well
REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 133,161,1984 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 82277 No. of Facilities: 114 (estimated) No. of Industries: 4 No. of Occupations: 3 No. of Employees: 1130 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 82277 No. of Facilities: 1080 (estimated) No. of Industries: 5 No. of Occupations: 7 No. of Employees: 12808 (estimated) No. of Female Employees: 9012 (estimated)
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Safety Information
| Symbol |
GHS07 |
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| Signal Word | Warning |
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| Hazard Statements | H302 |
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| Precautionary Statements | P301 + P312 + P330 |
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| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
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| Hazard Codes | Xn:Harmful |
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| Risk Phrases | R22;R36/37/38 |
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| Safety Phrases | S26-S36-S36/37/39 |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 3 |
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| RTECS | CD2480000 |
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| HS Code | 29331190 |
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