Basic information Safety Related Supplier

ChemicalBook Product Catalog Chemical Reagents Organic reagents fatty acid 4-?Hydroxyphenylpyruvic acid

1/1

4-?Hydroxyphenylpyruvic acid NEW

$35.00 50mg

$50.00 100mg

Min. Order
Purity99.22%
Cas No156-39-8
Supply Ability10g
Update time2026-04-13

TargetMol Chemicals Inc.

TargetMol Chemicals Inc.

VIP6Y

United States

United States

show more

Enterprise Verified

Business Bank account Basic Contact Infomation Business Address Trade Company

Chemical Properties

Product Name	4-?Hydroxyphenylpyruvic acid
CAS No	156-39-8
EC-No
Min. Order
Purity	99.22%
Supply Ability	10g
Release date	2026/04/13

Product Introduction

Bioactivity

Name	4-Hydroxyphenylpyruvic acid
Description	4-Hydroxyphenylpyruvic acid is an enzyme inhibitor.4-Hydroxyphenylpyruvic acid (4-HPPA) is a keto acid that is involved in the tyrosine catabolism pathway. It is a product of the enzyme (R)-4-hydroxyphenyllactate dehydrogenase (EC 1.1.1.222) and is formed during tyrosine metabolism. The conversion from tyrosine to 4-HPPA is catalyzed by tyrosine aminotransferase. Additionally, 4-HPPA can be converted to homogentisic acid which is one of the precursors to ochronotic pigment. The enzyme 4-hydroxyphenylpyruvic acid dioxygenase (HPD) catalyzes the reaction that converts 4-hydroxyphenylpyruvic acid to homogentisic acid. A deficiency in the catalytic activity of HPD is known to lead to tyrosinemia type III, an autosomal recessive disorder characterized by elevated levels of blood tyrosine and massive excretion of tyrosine derivatives into urine. It has been shown that hawkinsinuria, an autosomal dominant disorder characterized by the excretion of 'hawkinsin,' may also be a result of HPD deficiency . Moreover, 4-hydroxyphenylpyruvic acid is also found to be associated in phenylketonuria, which is also an inborn error of metabolism. There are two isomers of HPPA, specifically 4HPPA and 3HPPA, of which 4HPPA is the most common.
Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information	10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (11.1 mM), Sonication is recommended. DMSO : 125 mg/mL (693.83 mM), Sonication is recommended.
Keywords	Inhibitor \| inhibit \| Human Endogenous Metabolite \| EndogenousMetabolite \| Endogenous Metabolite \| 4-?Hydroxyphenylpyruvic acid \| 4Hydroxyphenylpyruvic acid \| 4 Hydroxyphenylpyruvic acid
Inhibitors Related	Sucrose \| Aceglutamide \| Nicotinamide riboside malate \| DL-Lysine \| D(+)-Raffinose pentahydrate \| Guanidine hydrochloride \| Malic acid \| Formamide \| Glycerol \| Thymidine \| Corn starch \| Gluconate Calcium
Related Compound Libraries	Bioactive Compound Library \| Natural Product Library \| Inhibitor Library \| Tobacco Monomer Library \| NO PAINS Compound Library \| Natural Product Library for HTS \| Immunology/Inflammation Compound Library \| Human Endogenous Metabolite Library \| Human Endogenous Metabolite Compound Library Plus \| Bioactive Compounds Library Max \| Gut Microbial Metabolite Library \| Human Metabolite Library

show more

Company Profile Introduction

You may like

Recommended supplier

Send Inquriy