1. Materials information
Use of 4,7,10-TRIOXA-1,13-TRIDECANEDIAMINE
PROTAC Linker 24 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 24 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
4,7,10-TRIOXA-1,13-TRIDECANEDIAMINE Biological Activity
| Description | PROTAC Linker 24 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 24 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
|---|
| Related Catalog | Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker |
|---|
| Target | Alkyl/ether |
|---|
| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. |
|---|
Chemical & Physical Properties
| Density | 1.0±0.1 g/cm3 |
|---|
| Boiling Point | 310.6±0.0 °C at 760 mmHg |
|---|
| Melting Point | -32 °C |
|---|
| Molecular Formula | C10H24N2O3 |
|---|
| Molecular Weight | 220.309 |
|---|
| Flash Point | 148.0±17.4 °C |
|---|
| Exact Mass | 220.178696 |
|---|
| PSA | 79.73000 |
|---|
| LogP | -1.51 |
|---|
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
|---|
| Index of Refraction | 1.464 |
|---|
2. Packaging of materials
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping & Delivery
Provide door to door service
Suitable for goods under 50kg
Delivery: 3-7 days
Cost: low cost
Provide airport to airport service
Suitable for goods over 50kg
Delivery: 3-14 days
Cost: high cost
Provide seaport to seaport service
Suitable for goods over 100kg
Delivery: 2-45 days
Cost: low cost
4. Contact information
For more details, pls contact us freely.
Email address: elin@fdachem.com
Mob: 86 13613820652
WhatsApp/Skype/Wechat/LINE: 86 13613820652
China
