5-Amino-1-methylquinolin-1-ium iodide NEW

Synonym: 5-amino-1-methylquinolin-1-ium iodide; 5-amino-1MQ; NNMTi; 5-Amino-1methylquinolinium iodide; 5-Amino-1-methylquinolinium

Appearance: Yellow to orange powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 2-8 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Shelf Life: >2 years if stored properly

Description: 5-amino-1MQ is a small molecule drug that functions to block the activity of an enzyme called nicotinamide N-methyltransferase (NNMT). NNMT plays a significant role in metabolism and energy and is predominantly active in fat tissue. By blocking NNMT, 5-amino-1MQ stimulates an increase in nicotinamide adenine dinucleotide (NAD+), a cofactor that is central to cellular metabolism, thereby increasing metabolic rate and activating a gene called sirtuin-1 (SIRT1). SIRT1 is also known as 'the longevity gene' because of its role in reducing the risk of diabetes, obesity, metabolic syndrome, atherosclerosis and other forms of cardiovascular disease, kidney disease, liver disease,  neurodegeneration, and cancer.