7-Deaza-2'-deoxyguanosine NEW

$0.00 10g

$0.00 50g

Min. Order10g
Purity97%
Cas No86392-75-8
Supply Ability100kg
Update time2026-04-14

Wuhan Fortuna Chemical Co., Ltd

VIP5Y

China

Since:2006-04-03

Address:Room 2015, No.2 Building Kaixin Mansion, No.107 Jinqiao Ave, Wuhan, China

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Chemical Properties

Product Name	7-Deaza-2'-deoxyguanosine
CAS No	86392-75-8
EC-No	500-100-4
Min. Order	10g
Purity	97%
Supply Ability	100kg
Release date	2026/04/14

7-Deaza-2'-deoxyguanosine is a synthetic nucleoside analog derived from deoxyguanosine (a DNA building block). Here's a concise breakdown:

Key Features:

Structural Modification:

The nitrogen atom at position 7 (N7) of the guanine base is replaced with carbon (C7).
The sugar moiety remains 2'-deoxyribose.
Functional Impact:

Disrupts Hoogsteen bonding: Lacks N7, critical for major-groove interactions (e.g., G-quadruplexes).
Maintains Watson-Crick pairing: Still pairs with cytosine (C), but with altered stability.
Enhanced stability: Resists enzymatic degradation better than natural deoxyguanosine.
Primary Applications:

DNA Sequencing: Reduces band compression artifacts in Sanger sequencing (especially in GC-rich regions).
Therapeutic Development: Serves as a precursor for antiviral/anticancer drugs (e.g., carbovir analogs).
Biochemical Probes: Studies DNA polymerase kinetics, nucleic acid structures, and enzyme mechanisms.
Fluorescent Labeling: C7 position can be modified for attachment of fluorophores.
Note: Often used alongside analogs like 7-deaza-dATP to resolve complex DNA secondary structures.

Significance:

This modification enables more accurate DNA analysis and facilitates the design of novel therapeutics targeting viral replication or cancer.

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Company Profile Introduction

Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/Feed additives, Fine chemicals in distributing the products of our own company and affiliated enterprises, are the members of Hubei E-commerce Chamber. Our company has professional persons who major in chemical R&D and sicentific management, supply fine chemical products with high quality and close service, also supply custom-tailored products according to our clients' requirement. We have a positive and self-motivated management work team with a common philosophy, caring and commitment through teamwork, our team strive to achieve success in delighting our clients and ourselves. Since Wuhan Fortuna Chemical Co., Ltd founded, we continuously innovate our products and improve our service, sales network. Hence, we initiate the first sale mode on net in China, which is the retail trade of small package bring along wholesale of diversified management modes. Our products are exported widely to South Korea, Vietnam, Australia, Europe and South America, highly recommended by our clients.We insist on the management creed “Market is our compass, Quality is our life, Credit is our soul”. Clients’ trust is our forward powder, their satisfaction is our struggling goal.