ChemicalBook Product Catalog all-trans-4-Oxoretinoic acid

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all-trans-4-Oxoretinoic acid NEW

$2.00 100kg

$4.00 10kg

$6.00 1kg

Min. Order1kg
Purity99%
Cas No38030-57-8
Supply Ability100kg
Update time2026-04-17

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

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Chemical Properties

Product Name	all-trans-4-Oxoretinoic acid
CAS No	38030-57-8
EC-No
Min. Order	1kg
Purity	99%
Supply Ability	100kg
Release date	2026/04/17

PRODUCT INFORMATION

Common Name	all-trans-4-Oxoretinoic acid
CAS Number	38030-57-8	Molecular Weight	314.41900
Density	1.07g/cm3	Boiling Point	509.9ºC at 760 mmHg
Molecular Formula	C20H26O3	Melting Point	175-178°C
MSDS	N/A	Flash Point	276.3ºC

Purity		Quantity		Budget		Inquiry

Use of all-trans-4-Oxoretinoic acid

all-trans-4-Oxoretinoic acid, an active metabolite of vitamin A, induces gene transcription via binding to nuclear retinoic acid receptors (RARs).

Properties
Spectrum

Name	all-trans-4-oxoretinoic acid
Synonym	More Synonyms

Description	all-trans-4-Oxoretinoic acid, an active metabolite of vitamin A, induces gene transcription via binding to nuclear retinoic acid receptors (RARs).
Related Catalog	Natural Products >> Others Research Areas >> Metabolic Disease
Target	Human Endogenous Metabolite
In Vitro	all-trans-4-Oxoretinoic acid, an active metabolite of vitamin A, induces gene transcription via binding to nuclear retinoic acid receptors (RARs)[1]. all-trans-4-Oxoretinoic acid is a biologically active geometric isomer of retinoic acid (RA) [2].
References	[1]. Topletz AR, et al. Induction of CYP26A1 by metabolites of retinoic acid: evidence that CYP26A1 is an important enzyme in the elimination of active retinoids. Mol Pharmacol. 2015;87(3):430-41. [2]. Stahl W, et al. 4-oxo-retinoic acid is generated from its precursor canthaxanthin and enhances gap junctional communication in 10T1/2 cells. Adv Exp Med Biol. 1996;387:121-8.

Density	1.07g/cm3
Boiling Point	509.9ºC at 760 mmHg
Melting Point	175-178°C
Molecular Formula	C20H26O3
Molecular Weight	314.41900
Flash Point	276.3ºC
Exact Mass	314.18800
PSA	54.37000
LogP	4.78160
Index of Refraction	1.565
Storage condition	2-8℃

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VH6599800

CHEMICAL NAME :
Retinoic acid, 4-oxo-

CAS REGISTRY NUMBER :
38030-57-8

LAST UPDATED :
199007

DATA ITEMS CITED :
5

MOLECULAR FORMULA :
C20-H26-O3

MOLECULAR WEIGHT :
314.46

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :
Oral

DOSE :
100 mg/kg

SEX/DURATION :
female 11 day(s) after conception

TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - musculoskeletal system

REFERENCE :
TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 35,33A,1987

TYPE OF TEST :
TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :
Oral

DOSE :
10 mg/kg

SEX/DURATION :
female 11 day(s) after conception

TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - musculoskeletal system

REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 100,162,1989

TYPE OF TEST :
TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :
Oral

DOSE :
20 mg/kg

SEX/DURATION :
female 8 day(s) after conception

TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 95,122,1988

TYPE OF TEST :
TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :
Oral

DOSE :
39 mg/kg

SEX/DURATION :
female 8 day(s) after conception

TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 95,122,1988

TYPE OF TEST :
TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :
Oral

DOSE :
4900 ug/kg

SEX/DURATION :
female 8 day(s) after conception

TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - other developmental abnormalities

REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 95,122,1988

4-Keto 13-cis-R...

CAS#:71748-57-7

~87%

all-trans-4-Oxo...

CAS#:38030-57-8

Literature: Mironova; Leont'eva; Shevyakov; Alexeeva; Shvets; Demina; Krasnokutskaya; Finkel'shtein; Khodonov Russian Journal of Bioorganic Chemistry, 2002 , vol. 28, # 6 p. 487 - 493

4-Hydroxyretino...

CAS#:38030-59-0

all-trans-4-Oxo...

CAS#:38030-57-8

Literature: Rosenberger Journal of Organic Chemistry, 1982 , vol. 47, # 9 p. 1698 - 1701

ethyl (2E,4E,6E...

CAS#:81121-19-9

all-trans-4-Oxo...

CAS#:38030-57-8

Literature: Rosenberger Journal of Organic Chemistry, 1982 , vol. 47, # 9 p. 1698 - 1701

Precursor 9	Previous 1/3 Next
CAS#:71748-57-7 4-Keto 13-cis-R... CAS#:38030-59-0 4-Hydroxyretino... CAS#:81121-19-9 ethyl (2E,4E,6E... CAS#:72526-76-2 ethyl (2E,6E,8E...
DownStream 1
CAS#:66592-72-1 4-Hydroxyretino...

4-keto-Retinoic Acid

4-oxo-all-rans-retinoic acid

4-Oxoretinoic Acid

all-trans-4-Oxoretinoic Acid

4-oxo-all-trans-retinoic acid

all-trans 4-Keto Retinoic Acid

4-oxo-Retinoic acid

4-Ketoretinoic Acid

4-Oxo-atRA

4-Oxotretinoin

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all-trans-4-Oxoretinoic acid NEW

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