Product Overview
Allopregnanolone (CAS: 516-54-1), a neuroactive steroid, is a potent endogenous modulator of GABA<sub>A</sub> receptors. It regulates neuronal excitability and stress responses, making it critical for treating neurological disorders like postpartum depression and epilepsy. This white crystalline powder also serves as a key ingredient in anti-aging cosmetics and pharmaceutical research intermediates.
✨ Key Advantages
✅ High Purity: ≥99% purity (HPLC/GC tested) for pharmaceutical and research applications.
✅ Neuroprotective Activity: Demonstrates EC<sub>50</sub> values of 10-50 nM in GABA<sub>A</sub> receptor modulation.
✅ Thermal Stability: Melting point 176-178°C ensures stability during formulation and storage.
🔬 Application Fields
Pharmaceuticals: Core component in treatments for postpartum depression, epilepsy, and neurodegenerative diseases.
Cosmetics: Enhances anti-aging formulations by promoting cellular repair and skin resilience.
Research: Vital for neurosteroid studies and drug development targeting GABA pathways.
📜 Quality Assurance
Produced in GMP-certified facilities with compliance to EP/USP standards.
Rigorous quality control via HPLC, NMR, and mass spectrometry for batch consistency.
Complies with MSDS safety guidelines for safe handling and storage.
📈 Market Insights
The global neurosteroid market is projected to grow at a CAGR of 7.8% (2025-2030), driven by rising demand for non-hormonal antidepressants and neurological therapies. Allopregnanolone’s role in the $1.2B postpartum depression treatment market underscores its commercial significance.
China
