PRODUCT INFORMATION
| Common Name | Amino-PEG6-alcohol |
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| CAS Number | 39160-70-8 | Molecular Weight | 281.346 |
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| Density | 1.1±0.1 g/cm3 | Boiling Point | 388.0±37.0 °C at 760 mmHg |
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| Molecular Formula | C12H27NO6 | Melting Point | N/A |
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| MSDS | N/A | Flash Point | 188.5±26.5 °C |
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Use of Amino-PEG6-alcohol
Amino-PEG6-OH is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
Names
| Name | 1-Aminohexaethylene Glycol |
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| Synonym | More Synonyms |
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Amino-PEG6-alcohol Biological Activity
| Description | Amino-PEG6-OH is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
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| Related Catalog | Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker |
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| Target | Cleavable |
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| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
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| References | [1]. Yong Zu Kim, et al. Antibody-drug conjugates comprising branched linkers and methods related thereto. WO2017089895A1. |
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Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
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| Boiling Point | 388.0±37.0 °C at 760 mmHg |
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| Molecular Formula | C12H27NO6 |
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| Molecular Weight | 281.346 |
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| Flash Point | 188.5±26.5 °C |
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| Exact Mass | 281.183838 |
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| PSA | 92.40000 |
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| LogP | -2.80 |
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| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
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| Index of Refraction | 1.463 |
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| Storage condition | 2-8°C |
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Precursor & DownStream
| Precursor 8 | Previous 1/2 Next |
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 CAS#:86770-69-6
Azido-PEG6-alcohol
 CAS#:2615-15-8
hexaethyleneglycol
 CAS#:352439-34-0
17-hydroxy-3,6,...
 CAS#:1663-39-4
tert-Butyl acrylate
|
| DownStream 0 |
|
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Synonyms
| 3,6,9,12,15-Pentaoxaheptadecan-1-ol, 17-amino- |
| 17-Amino-3,6,9,12,15-pentaoxaheptadecan-1-ol |
| 2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanol |
| Amino-PEG6-alcohol |
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